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DDX3 Regulates Cell Growth through Translational Control of Cyclin E1

DDX3 belongs to the DEAD box family of RNA helicases, but the details of its biological function remain largely unclear. Here we show that knockdown of DDX3 expression impedes G(1)/S-phase transition of the cell cycle. To know how DDX3 may act in cell cycle control, we screened for cellular mRNA tar...

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Main Authors: Lai, Ming-Chih, Chang, Wen-Cheng, Shieh, Sheau-Yann, Tarn, Woan-Yuh
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology (ASM) 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976371/
https://ncbi.nlm.nih.gov/pubmed/20837705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00560-10
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