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DDX3 Regulates Cell Growth through Translational Control of Cyclin E1

DDX3 belongs to the DEAD box family of RNA helicases, but the details of its biological function remain largely unclear. Here we show that knockdown of DDX3 expression impedes G(1)/S-phase transition of the cell cycle. To know how DDX3 may act in cell cycle control, we screened for cellular mRNA tar...

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Detalhes bibliográficos
Main Authors: Lai, Ming-Chih, Chang, Wen-Cheng, Shieh, Sheau-Yann, Tarn, Woan-Yuh
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976371/
https://ncbi.nlm.nih.gov/pubmed/20837705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00560-10
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