Identification of a transcriptional silencer in the 5'-flanking region of the human epsilon-globin gene.
We have studied the 5'-flanking sequences required for the transcriptional regulation of human epsilon-globin gene expression. A series of deletion mutants of the human epsilon-globin gene 5'-flanking sequences were constructed and linked to the bacterial chloramphenicol acetyltransferase gene. Expr...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
1989
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297610/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2748586/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.14.5306 |
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