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Identification of a transcriptional silencer in the 5'-flanking region of the human epsilon-globin gene.

We have studied the 5'-flanking sequences required for the transcriptional regulation of human epsilon-globin gene expression. A series of deletion mutants of the human epsilon-globin gene 5'-flanking sequences were constructed and linked to the bacterial chloramphenicol acetyltransferase gene. Expr...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Cao, S X, Gutman, P D, Dave, H P, Schechter, A N
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1989
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297610/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2748586/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.14.5306
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