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Revealing the structural basis of action of hERG potassium channel activators and blockers
Human ether-á-go-go related gene (hERG) potassium (K(+)) channels play a critical role in cardiac action potential repolarization. This is due, in large part, to the unique gating properties of these channels, which are characterized by relatively slow activation and an unusually fast and voltage-de...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Blackwell Science Inc
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2976011/ https://ncbi.nlm.nih.gov/pubmed/20643767 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2010.194670 |
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