SPLUNC1 expression reduces surface levels of the epithelial sodium channel (ENaC) in Xenopus laevis oocytes

Throughout the body, the epithelial Na(+) channel (ENaC) plays a critical role in salt and liquid homeostasis. In cystic fibrosis airways, for instance, improper regulation of ENaC results in hyperabsorption of sodium that causes dehydration of airway surface liquid. This dysregulation then contribu...

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Bibliografiske detaljer
Main Authors: Rollins, Brett M, Garcia-Caballero, Agustin, Stutts, M Jackson, Tarran, Robert
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2010
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Article Addendum
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975823/
https://ncbi.nlm.nih.gov/pubmed/20519934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chan.4.4.12255
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