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FOCAL EXPRESSION OF MUTATED TAU IN ENTORHINAL CORTEX NEURONS OF RATS IMPAIRS SPATIAL WORKING MEMORY

Entorhinal cortex neuropathology begins very early in Alzheimer's disease (AD), a disorder characterized by severe memory disruption. Indeed, loss of entorhinal volume is predictive of AD and two of the hallmark neuroanatomical markers of AD, amyloid plaques and neurofibrillary tangles (NFTs),...

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Autors principals: Ramirez, Julio J., Poulton, Winona E., Knelson, Erik, Barton, Cole, King, Michael A., Klein, Ronald L.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975819/
https://ncbi.nlm.nih.gov/pubmed/20727915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2010.08.013
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