Modulating cholesteryl ester transfer protein activity maintains efficient pre-β-HDL formation and increases reverse cholesterol transport

The mechanism by which cholesteryl ester transfer protein (CETP) activity affects HDL metabolism was investigated using agents that selectively target CETP (dalcetrapib, torcetrapib, anacetrapib). In contrast with torcetrapib and anacetrapib, dalcetrapib requires cysteine 13 to decrease CETP activit...

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Main Authors: Niesor, Eric J., Magg, Christine, Ogawa, Naoto, Okamoto, Hiroshi, von der Mark, Elisabeth, Matile, Hugues, Schmid, Georg, Clerc, Roger G., Chaput, Evelyne, Blum-Kaelin, Denise, Huber, Walter, Thoma, Ralf, Pflieger, Philippe, Kakutani, Makoto, Takahashi, Daisuke, Dernick, Gregor, Maugeais, Cyrille
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Biochemistry and Molecular Biology 2010
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Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975716/
https://ncbi.nlm.nih.gov/pubmed/20861162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M008706
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