NIK Stabilization in Osteoclasts Results in Osteoporosis and Enhanced Inflammatory Osteolysis

BACKGROUND: Maintenance of healthy bone requires the balanced activities of osteoclasts (OCs), which resorb bone, and osteoblasts, which build bone. Disproportionate action of OCs is responsible for the bone loss associated with postmenopausal osteoporosis and rheumatoid arthritis. NF-κB inducing ki...

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Détails bibliographiques
Auteurs principaux: Yang, Chang, McCoy, Kathleen, Davis, Jennifer L., Schmidt-Supprian, Marc, Sasaki, Yoshiteru, Faccio, Roberta, Novack, Deborah Veis
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2010
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975662/
https://ncbi.nlm.nih.gov/pubmed/21151480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015383
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