NIK Stabilization in Osteoclasts Results in Osteoporosis and Enhanced Inflammatory Osteolysis

BACKGROUND: Maintenance of healthy bone requires the balanced activities of osteoclasts (OCs), which resorb bone, and osteoblasts, which build bone. Disproportionate action of OCs is responsible for the bone loss associated with postmenopausal osteoporosis and rheumatoid arthritis. NF-κB inducing ki...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Yang, Chang, McCoy, Kathleen, Davis, Jennifer L., Schmidt-Supprian, Marc, Sasaki, Yoshiteru, Faccio, Roberta, Novack, Deborah Veis
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2010
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975662/
https://ncbi.nlm.nih.gov/pubmed/21151480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015383
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