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HMMSplicer: A Tool for Efficient and Sensitive Discovery of Known and Novel Splice Junctions in RNA-Seq Data
BACKGROUND: High-throughput sequencing of an organism's transcriptome, or RNA-Seq, is a valuable and versatile new strategy for capturing snapshots of gene expression. However, transcriptome sequencing creates a new class of alignment problem: mapping short reads that span exon-exon junctions b...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
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Public Library of Science
2010
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2975632/ https://ncbi.nlm.nih.gov/pubmed/21079731 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013875 |
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