PPARγ mediates a direct anti-angiogenic effect of ω3-PUFAs in proliferative retinopathy

RATIONALE: Omega3 long-chain polyunsaturated fatty acids (ω3-PUFAs) are powerful modulators of angiogenesis. However, little is known about the mechanisms governing ω3-PUFA-dependent attenuation of angiogenesis. OBJECTIVE: This study aims to identify a major mechanism by which ω3-PUFAs attenuate ret...

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Hlavní autoři: Stahl, Andreas, Sapieha, Przemyslaw, Connor, Kip M., SanGiovanni, John Paul, Chen, Jing, Aderman, Christopher M., Willett, Keirnan L., Krah, Nathan M., Dennison, Roberta J., Seaward, Molly R., Guerin, Karen I., Hua, Jing, Smith, Lois E. H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975617/
https://ncbi.nlm.nih.gov/pubmed/20634487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.110.221317
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