Cerebral dynamics and metabolism of hyperpolarized [1-(13)C]pyruvate using time-resolved MR spectroscopic imaging

Dynamic hyperpolarized [1-(13)C]pyruvate metabolic imaging in the normal anesthetized rat brain is demonstrated on a clinical 3-T magnetic resonance imaging scanner. A 12-second bolus injection of hyperpolarized [1-(13)C]pyruvate is imaged at a 3-second temporal resolution. The observed dynamics are...

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Detalhes bibliográficos
Main Authors: Hurd, Ralph E, Yen, Yi-Fen, Tropp, James, Pfefferbaum, Adolf, Spielman, Daniel M, Mayer, Dirk
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975615/
https://ncbi.nlm.nih.gov/pubmed/20588318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2010.93
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