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T-jump and Fast Photochemical Oxidation Probe Sub Millisec Protein Folding
We report a new mass spectrometry-based approach to study protein-folding dynamics at the sub millisecond time. The strategy couples temperature jump with fast photochemical oxidation of proteins (FPOP) whereby folding/unfolding is followed by changes in oxidative modifications by OH radical reactio...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2975609/ https://ncbi.nlm.nih.gov/pubmed/20958033 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja106518d |
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