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Fast Photochemical Oxidation of Proteins Footprints Faster than Protein Unfolding

Fast photochemical oxidation of proteins (FPOP) is a chemical footprinting method whereby exposed amino-acid residues are covalently labeled by oxidation with hydroxyl radicals produced by the photolysis of hydrogen peroxide. Modified residues can be detected by standard trypsin proteolysis followed...

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Main Authors: Gau, Brian C., Sharp, Joshua S., Rempel, Don L., Gross, Michael L.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164994/
https://ncbi.nlm.nih.gov/pubmed/20337372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac901054w
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