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Phenotypic Reversion or Death of Cancer Cells by Altering Signaling Pathways in Three-Dimensional Contexts

BACKGROUND: We previously used a three-dimensional (3D) reconstituted basement membrane (rBM) assay to demonstrate that tumorigenic HMT-3522 T4–2 human breast cells can be induced to form morphologically normal structures (“reversion”) by treatment with inhibitors of β1 integrin, the epidermal growt...

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書誌詳細
主要な著者: Wang, Fei, Hansen, Rhonda K., Radisky, Derek, Yoneda, Toshiyuki, Barcellos-Hoff, Mary Helen, Petersen, Ole W., Turley, Eva A., Bissell, Mina J.
フォーマット: Artigo
言語:Inglês
出版事項: 2002
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975573/
https://ncbi.nlm.nih.gov/pubmed/12359858
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