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Estrogen and progesterone receptors have distinct roles in the establishment of the hyperplastic phenotype in PR-A transgenic mice

INTRODUCTION: Expression of the A and B forms of progesterone receptor (PR) in an appropriate ratio is critical for mammary development. Mammary glands of PR-A transgenic mice, carrying an additional A form of PR as a transgene, exhibit morphological features associated with the development of mamma...

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Detalhes bibliográficos
Main Authors: Simian, Marina, Bissell, Mina J, Barcellos-Hoff, Mary Helen, Shyamala, Gopalan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790852/
https://ncbi.nlm.nih.gov/pubmed/19788752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2408
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