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Short, direct repeats at the breakpoints of deletions of the retinoblastoma gene.

We found deletions involving the retinoblastoma gene in 12 of 49 tumors from patients with retinoblastoma or osteosarcoma. After mapping the deletion breakpoints, we found that no two breakpoints coincided. Thus, our data do not support the conclusions of others regarding the existence of a "hotspot...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Canning, S, Dryja, T P
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 1989
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297553/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2740342/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.13.5044
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