Short, direct repeats at the breakpoints of deletions of the retinoblastoma gene.
We found deletions involving the retinoblastoma gene in 12 of 49 tumors from patients with retinoblastoma or osteosarcoma. After mapping the deletion breakpoints, we found that no two breakpoints coincided. Thus, our data do not support the conclusions of others regarding the existence of a "hotspot...
Guardat en:
| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1989
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297553/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2740342/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.13.5044 |
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