Short, direct repeats at the breakpoints of deletions of the retinoblastoma gene.
We found deletions involving the retinoblastoma gene in 12 of 49 tumors from patients with retinoblastoma or osteosarcoma. After mapping the deletion breakpoints, we found that no two breakpoints coincided. Thus, our data do not support the conclusions of others regarding the existence of a "hotspot...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1989
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297553/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2740342/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.13.5044 |
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