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Conditions Under Which Genome-Wide Association Studies Will be Positively Misleading

Genome-wide association mapping is a popular method for using natural variation within a species to generate a genotype–phenotype map. Statistical association between an allele at a locus and the trait in question is used as evidence that variation at the locus is responsible for variation of the tr...

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Hlavní autoři: Platt, Alexander, Vilhjálmsson, Bjarni J., Nordborg, Magnus
Médium: Artigo
Jazyk:Inglês
Vydáno: Genetics Society of America 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975277/
https://ncbi.nlm.nih.gov/pubmed/20813880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.110.121665
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