AMP-activated Protein Kinase Mediates Apoptosis in Response to Bioenergetic Stress through Activation of the Pro-apoptotic Bcl-2 Homology Domain-3-only Protein BMF

Heterozygous loss-of-function mutations in the hepatocyte nuclear factor 1A (HNF1A) gene result in the pathogenesis of maturity-onset diabetes-of-the-young type 3, (HNF1A-MODY). This disorder is characterized by a primary defect in metabolism-secretion coupling and decreased beta cell mass, attribut...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Kilbride, Seán M., Farrelly, Angela M., Bonner, Caroline, Ward, Manus W., Nyhan, Kristine C., Concannon, Caoimhín G., Wollheim, Claes B., Byrne, Maria M., Prehn, Jochen H. M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975242/
https://ncbi.nlm.nih.gov/pubmed/20841353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.138107
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados