Regulation of cAMP-dependent Protein Kinases: THE HUMAN PROTEIN KINASE X (PrKX) REVEALS THE ROLE OF THE CATALYTIC SUBUNIT αH-αI LOOP

cAMP-dependent protein kinases are reversibly complexed with any of the four isoforms of regulatory (R) subunits, which contain either a substrate or a pseudosubstrate autoinhibitory domain. The human protein kinase X (PrKX) is an exemption as it is inhibited only by pseudosubstrate inhibitors, i.e....

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Detalhes bibliográficos
Main Authors: Diskar, Mandy, Zenn, Hans-Michael, Kaupisch, Alexandra, Kaufholz, Melanie, Brockmeyer, Stefanie, Sohmen, Daniel, Berrera, Marco, Zaccolo, Manuela, Boshart, Michael, Herberg, Friedrich W., Prinz, Anke
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975214/
https://ncbi.nlm.nih.gov/pubmed/20819953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.155150
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