Polymeric Immunoglobulin Receptor-mediated Invasion of Streptococcus pneumoniae into Host Cells Requires a Coordinate Signaling of SRC Family of Protein-tyrosine Kinases, ERK, and c-Jun N-terminal Kinase

Streptococcus pneumoniae are commensals of the human nasopharynx with the capacity to invade mucosal respiratory cells. PspC, a pneumococcal surface protein, interacts with the human polymeric immunoglobulin receptor (pIgR) to promote bacterial adherence to and invasion into epithelial cells. Intern...

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Detalhes bibliográficos
Main Authors: Agarwal, Vaibhav, Asmat, Tauseef M., Dierdorf, Nina I., Hauck, Christof R., Hammerschmidt, Sven
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975186/
https://ncbi.nlm.nih.gov/pubmed/20829350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.172999
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