Rad9 Is Required for B Cell Proliferation and Immunoglobulin Class Switch Recombination

B cell maturation and B cell-mediated antibody response require programmed DNA modifications such as the V(D)J recombination, the immunoglobulin (Ig) class switch recombination, and the somatic hypermutation to generate functional Igs. Many protein factors involved in DNA damage repair have been sho...

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Detalhes bibliográficos
Main Authors: An, Lili, Wang, Yulan, Liu, Yuheng, Yang, Xiao, Liu, Chunchun, Hu, Zhishang, He, Wei, Song, Wenxia, Hang, Haiying
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975150/
https://ncbi.nlm.nih.gov/pubmed/20729201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.161208
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