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Use of the spliceosomal protein U1A to facilitate crystallization and structure determination of complex RNAs
The structure determination of complex RNA molecules such as ribozymes, riboswitches and aptamers by X-ray crystallography hinges on the preparation of well-ordered crystals. Success usually results from molecular engineering to facilitate crystallization. An approach that has resulted in ten new RN...
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2974902/ https://ncbi.nlm.nih.gov/pubmed/20554048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2010.06.008 |
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