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Factor V Is an Anticoagulant Cofactor for Activated Protein C during Inactivation of Factor Va
Coagulation factor V (FV) promotes inactivation of activated factor VIII (FVIIIa) by activated protein C (APC) and protein S. Loss of this APC cofactor activity is proposed to be partially responsible for the APC resistance phenotype of FV(Leiden). However, FVIIIa loses activity rapidly due to disso...
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| Hoofdauteurs: | , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
S. Karger AG
2010
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2974842/ https://ncbi.nlm.nih.gov/pubmed/20501981 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000315141 |
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