Immune activation induces immortalization of HTLV-1 LTR-Tax transgenic CD4(+) T cells

Infection with the human T-cell leukemia virus-1 (HTLV-1) results in a variety of diseases including adult T-cell leukemia/lymphoma (ATL). Although the pathogenesis of these disorders is poorly understood, it involves complex interactions with the host immune system. Activation of infected T cells m...

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Main Authors: Swaims, Alison Y., Khani, Francesca, Zhang, Yingyu, Roberts, Arthur I., Devadas, Satish, Shi, Yufang, Rabson, Arnold B.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2010
Assuntos:
Lymphoid Neoplasia
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2974607/
https://ncbi.nlm.nih.gov/pubmed/20634377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-07-231050
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