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Optimization of ex vivo hematopoietic stem cell expansion in intermittent dynamic cultures

For the ex vivo expansion of CD34(+) cells, culture conditions were optimized using cytokine cocktails and media change methods. In addition, static, orbital-shake, and stirred cultures were compared. After cultivation, total cell expansion, immunophenotypes, clonogenic ability, and metabolite conce...

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Bibliografske podrobnosti
Main Authors: Choi, Yong-Soo, Noh, Sang-Eun, Lim, Sang-Min, Kim, Dong-il
Format: Artigo
Jezik:Inglês
Izdano: Springer Netherlands 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2974206/
https://ncbi.nlm.nih.gov/pubmed/20652621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10529-010-0355-0
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