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Chromosomal mapping of pancreatic islet morphological features and regulatory hormones in the spontaneously diabetic (Type 2) Goto-Kakizaki rat

Insulin resistance and altered endocrine pancreas function are central pathophysiological features of type 2 diabetes mellitus (T2DM). The Goto-Kakizaki (GK) rat is a model of spontaneous T2DM characterised by reduced beta cell mass and genetically determined glucose intolerance and altered insulin...

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Detalhes bibliográficos
Main Authors: Finlay, Clare, Argoud, Karène, Wilder, Steven P., Ouali, Fetta, Ktorza, Alain, Kaisaki, Pamela J., Gauguier, Dominique
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2974204/
https://ncbi.nlm.nih.gov/pubmed/20878524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00335-010-9285-3
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