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Ultrasound-assisted powder-coating technique to improve content uniformity of low-dose solid dosage forms

An ultrasound-assisted powder-coating technique was used to produce a homogeneous powder formulation of a low-dose active pharmaceutical ingredient (API). The powdered particles of microcrystalline cellulose (MCC; Avicel(®) PH-200) were coated with a 4% m/V aqueous solution of riboflavin sodium phos...

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Détails bibliographiques
Auteurs principaux: Genina, Natalja, Räikkönen, Heikki, Antikainen, Osmo, Heinämäki, Jyrki, Yliruusi, Jouko
Format: Artigo
Langue:Inglês
Publié: Springer US 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2974109/
https://ncbi.nlm.nih.gov/pubmed/20730575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-010-9514-9
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