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Crystal Morphology Engineering of Pharmaceutical Solids: Tabletting Performance Enhancement

Crystal morphology engineering of a macrolide antibiotic, erythromycin A dihydrate, was investigated as a tool for tailoring tabletting performance of pharmaceutical solids. Crystal habit modification was induced by using a common pharmaceutical excipient, hydroxypropyl cellulose, as an additive dur...

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Bibliografiske detaljer
Main Authors: Mirza, Sabiruddin, Miroshnyk, Inna, Heinämäki, Jyrki, Antikainen, Osmo, Rantanen, Jukka, Vuorela, Pia, Vuorela, Heikki, Yliruusi, Jouko
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663677/
https://ncbi.nlm.nih.gov/pubmed/19184449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-009-9187-4
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