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Human Rhabdomyosarcomas secrete MIF that modulates metastatic behavior of tumor cells and inhibits recruitment of Cancer Associated Fibroblasts
The overexpression of macrophage migration inhibitory factor (MIF) has been observed in many tumors and is implicated in oncogenic transformation and tumor progression. MIF activates CXCR2 and CD74 receptors, and as recently reported, may also bind to the stromal-derived factor-1 (SDF-1)–binding rec...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2974061/ https://ncbi.nlm.nih.gov/pubmed/20861157 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-10-0288 |
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