Anti-Tumor Effect in Human Lung Cancer by a Combination Treatment of Novel Histone Deacetylase Inhibitors: SL142 or SL325 and Retinoic Acids

Histone deacetylase (HDAC) inhibitors arrest cancer cell growth and cause apoptosis with low toxicity thereby constituting a promising treatment for cancer. In this study, we investigated the anti-tumor activity in lung cancer cells of the novel cyclic amide-bearing hydroxamic acid based HDAC inhibi...

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Detalhes bibliográficos
Main Authors: Han, Shaoteng, Fukazawa, Takuya, Yamatsuji, Tomoki, Matsuoka, Junji, Miyachi, Hiroyuki, Maeda, Yutaka, Durbin, Mary, Naomoto, Yoshio
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2973950/
https://ncbi.nlm.nih.gov/pubmed/21079797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013834
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