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What differences are detected by superiority trials or ruled out by noninferiority trials? A cross-sectional study on a random sample of two-hundred two-arms parallel group randomized clinical trials

BACKGROUND: The smallest difference to be detected in superiority trials or the largest difference to be ruled out in noninferiority trials is a key determinant of sample size, but little guidance exists to help researchers in their choice. The objectives were to examine the distribution of differen...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Gayet-Ageron, Angèle, Agoritsas, Thomas, Combescure, Christophe, Bagamery, Krisztina, Courvoisier, Delphine S, Perneger, Thomas V
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2973934/
https://ncbi.nlm.nih.gov/pubmed/20950464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2288-10-93
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