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Neuronal Abelson helper integration site-1 (Ahi1) deficiency in mice alters TrkB signaling with a depressive phenotype

Recent studies suggest that the human Abelson helper integration site-1 (AHI1) gene on chromosome 6 is associated with susceptibility to schizophrenia and autism, two common neuropsychological disorders with depression symptoms. Mouse Ahi1 protein is abundant in the hypothalamus and amygdala, which...

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Detalhes bibliográficos
Main Authors: Xu, Xingshun, Yang, Hao, Lin, Yung-Feng, Li, Xiang, Cape, Austin, Ressler, Kerry J., Li, Shihua, Li, Xiao-Jiang
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2973903/
https://ncbi.nlm.nih.gov/pubmed/20956301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1013032107
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