Inhibition of the cation channel TRPV4 improves bladder function in mice and rats with cyclophosphamide-induced cystitis

Reduced functional bladder capacity and concomitant increased micturition frequency (pollakisuria) are common lower urinary tract symptoms associated with conditions such as cystitis, prostatic hyperplasia, neurological disease, and overactive bladder syndrome. These symptoms can profoundly affect t...

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Huvudupphovsmän: Everaerts, Wouter, Zhen, Xiaoguang, Ghosh, Debapriya, Vriens, Joris, Gevaert, Thomas, Gilbert, James P., Hayward, Neil J., McNamara, Colleen R., Xue, Fenqin, Moran, Magdalene M., Strassmaier, Timothy, Uykal, Eda, Owsianik, Grzegorz, Vennekens, Rudi, De Ridder, Dirk, Nilius, Bernd, Fanger, Christopher M., Voets, Thomas
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2010
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2973867/
https://ncbi.nlm.nih.gov/pubmed/20956320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1005333107
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