Inhibition of the cation channel TRPV4 improves bladder function in mice and rats with cyclophosphamide-induced cystitis

Reduced functional bladder capacity and concomitant increased micturition frequency (pollakisuria) are common lower urinary tract symptoms associated with conditions such as cystitis, prostatic hyperplasia, neurological disease, and overactive bladder syndrome. These symptoms can profoundly affect t...

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Detalhes bibliográficos
Main Authors: Everaerts, Wouter, Zhen, Xiaoguang, Ghosh, Debapriya, Vriens, Joris, Gevaert, Thomas, Gilbert, James P., Hayward, Neil J., McNamara, Colleen R., Xue, Fenqin, Moran, Magdalene M., Strassmaier, Timothy, Uykal, Eda, Owsianik, Grzegorz, Vennekens, Rudi, De Ridder, Dirk, Nilius, Bernd, Fanger, Christopher M., Voets, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2973867/
https://ncbi.nlm.nih.gov/pubmed/20956320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1005333107
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