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Quantifying the Impact of Human Immunodeficiency Virus-1 Escape From Cytotoxic T-Lymphocytes

HIV-1 escape from the cytotoxic T-lymphocyte (CTL) response leads to a weakening of viral control and is likely to be detrimental to the patient. To date, the impact of escape on viral load and CD4(+) T cell count has not been quantified, primarily because of sparse longitudinal data and the difficu...

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Detalhes bibliográficos
Main Authors: Kadolsky, Ulrich D., Asquith, Becca
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2973816/
https://ncbi.nlm.nih.gov/pubmed/21079675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000981
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