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Evaluating Gene Expression Dynamics Using Pairwise RNA FISH Data

Recently, a novel approach has been developed to study gene expression in single cells with high time resolution using RNA Fluorescent In Situ Hybridization (FISH). The technique allows individual mRNAs to be counted with high accuracy in wild-type cells, but requires cells to be fixed; thus, each c...

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Autori principali: Wyart, Matthieu, Botstein, David, Wingreen, Ned S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2973809/
https://ncbi.nlm.nih.gov/pubmed/21079668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000979
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