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c-Cbl-mediated degradation of TRAIL receptors is responsible for the development of the early phase of TRAIL resistance
We previously reported two modes of development of acquired TRAIL resistance: early phase and late phase [1]. In these studies, we observed that greater Akt activity and the expression of Bcl-xL were related mainly to the late phase of acquired TRAIL resistance. Recently we became aware of a possibl...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2973327/ https://ncbi.nlm.nih.gov/pubmed/19932172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2009.11.012 |
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