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Kinetics of G-protein–coupled receptor endosomal trafficking pathways revealed by single quantum dots

G-protein–coupled receptors (GPCRs) are the largest protein superfamily in the human genome; they comprise 30% of current drug targets and regulate diverse cellular signaling responses. The role of endosomal trafficking in GPCR signaling regulation is gaining substantial consideration. However, this...

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Detalles Bibliográficos
Autores principales: Fichter, Katye M., Flajolet, Marc, Greengard, Paul, Vu, Tania Q.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2972942/
https://ncbi.nlm.nih.gov/pubmed/20940319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1013763107
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