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Adaptation to diverse nitrogen-limited environments by deletion or extrachromosomal element formation of the GAP1 locus

To study adaptive evolution in defined environments, we performed evolution experiments with Saccharomyces cerevisiae (yeast) in nitrogen-limited chemostat cultures. We used DNA microarrays to identify copy-number variation associated with adaptation and observed frequent amplifications and deletion...

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Detalhes bibliográficos
Main Authors: Gresham, David, Usaite, Renata, Germann, Susanne Manuela, Lisby, Michael, Botstein, David, Regenberg, Birgitte
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2972935/
https://ncbi.nlm.nih.gov/pubmed/20937885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1014023107
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