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Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model
Synaptic dysfunction and the loss of synapses are early pathological features of Alzheimer's disease (AD). Synapses are sites of high energy demand and extensive calcium fluctuations; accordingly, synaptic transmission requires high levels of ATP and constant calcium fluctuation. Thus, synaptic...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2972922/ https://ncbi.nlm.nih.gov/pubmed/20937894 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1006586107 |
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