Φορτώνει......
Thrombospondin-1 supports blood pressure by limiting eNOS activation and endothelial-dependent vasorelaxation
AIMS: Thrombospondin-1 (TSP1), via its necessary receptor CD47, inhibits nitric oxide (NO)-stimulated soluble guanylate cyclase activation in vascular smooth muscle cells, and TSP1-null mice have increased shear-dependent blood flow compared with wild-type mice. Yet, the endothelial basement membran...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Oxford University Press
2010
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2972685/ https://ncbi.nlm.nih.gov/pubmed/20610415 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvq218 |
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