The Effect of Tribbles-Related Protein 3 on ER Stress-Suppressed Insulin Gene Expression in INS-1 Cells

BACKGROUND: The highly developed endoplasmic reticulum (ER) structure in pancreatic beta cells is heavily involved in insulin biosynthesis. Thus, any perturbation in ER function inevitably impacts insulin biosynthesis. Recent studies showed that the expression of tribbles-related protein 3 (TRB3), a...

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Main Authors: Jang, Young Yun, Kim, Nam Keong, Kim, Mi Kyung, Lee, Ho Young, Kim, Sang Jin, Kim, Hye Soon, Seo, Hye-Young, Lee, In Kyu, Park, Keun Gyu
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Diabetes Association 2010
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2972491/
https://ncbi.nlm.nih.gov/pubmed/21076579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4093/kdj.2010.34.5.312
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