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Role of astrocytic leptin receptor subtypes on leptin permeation across hCMEC/D3 human brain endothelial cells

Astrocytic leptin receptors (ObR) can be upregulated in conditions such as adult-onset obesity. To determine whether the levels and subtypes of astrocytic ObR modulate leptin transport, we co-cultured hCMEC/D3 human brain endothelial cells and C6 astrocytoma cells in the Transwell system, and tested...

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Autori principali: Hsuchou, Hung, Kastin, Abba J., Tu, Hong, Abbott, N. Joan, Couraud, Pierre-Olivier, Pan, Weihong
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2972375/
https://ncbi.nlm.nih.gov/pubmed/20977476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2010.07028.x
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