Oncogenic Src requires a wild-type counterpart to regulate invadopodia maturation

The proto-oncogene Src tyrosine kinase (Src) is overexpressed in human cancers and is currently a target of anti-invasive therapies. Activation of Src is an essential catalyst of invadopodia production. Invadopodia are cellular structures that mediate extracellular matrix (ECM) proteolysis, allowing...

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Detaylı Bibliyografya
Asıl Yazarlar: Kelley, Laura C., Ammer, Amanda Gatesman, Hayes, Karen E., Martin, Karen H., Machida, Kazuya, Jia, Lin, Mayer, Bruce J., Weed, Scott A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Company of Biologists 2010
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2972274/
https://ncbi.nlm.nih.gov/pubmed/20980387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.075200
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