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Oncogenic Src requires a wild-type counterpart to regulate invadopodia maturation
The proto-oncogene Src tyrosine kinase (Src) is overexpressed in human cancers and is currently a target of anti-invasive therapies. Activation of Src is an essential catalyst of invadopodia production. Invadopodia are cellular structures that mediate extracellular matrix (ECM) proteolysis, allowing...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Company of Biologists
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2972274/ https://ncbi.nlm.nih.gov/pubmed/20980387 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.075200 |
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