Mandatory fortification with folic acid in the United States appears to have adverse effects on histone methylation in women with pre-cancer but not in women free of pre-cancer

OBJECTIVE: To evaluate whether mandatory fortification of grain products with folic acid in the US is associated with changes in histone methylation in cells involved in cervical carcinogenesis. METHODS: Cervical specimens obtained before (1990 to 1992) and after mandatory folic acid fortification (...

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Detalhes bibliográficos
Main Authors: Piyathilake, Chandrika J, Macaluso, Maurizio, Celedonio, Jorge E, Badiga, Suguna, Bell, Walter C, Grizzle, William E
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2010
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2971712/
https://ncbi.nlm.nih.gov/pubmed/21072283
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