Pharmacokinetic Analysis of Polyamide Nucleic-Acid-Cell Penetrating Peptide Conjugates Targeted against HIV-1 Transactivation Response Element

We have demonstrated that polyamide nucleic acids complementary to the transactivation response (TAR) element of HIV-1 LTR inhibit HIV-1 production when transfected in HIV-1 infected cells. We have further shown that anti-TAR PNA (PNA(TAR)) conjugated with cell-penetrating peptide (CPP) is rapidly t...

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Bibliografske podrobnosti
Main Authors: Ganguly, Sabyasachi, Chaubey, Binay, Tripathi, Snehlata, Upadhyay, Alok, Neti, Prasad V.S.V., Howell, Roger W., Pandey, Virendra Nath
Format: Artigo
Jezik:Inglês
Izdano: Mary Ann Liebert, Inc. 2008
Teme:
Original Papers
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2971648/
https://ncbi.nlm.nih.gov/pubmed/18729823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/oli.2008.0140
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